Individualized Pharmaceutical Care for a Child with Infective Endocarditis and Osteomyelitis

Wang Siyun; Liang Dandan; Ma Jiulong; Zhai Lijie; Chai Jin; Fu Xiujuan; Li Xin

doi:10.13407/ j.cnki.jpp.1672-108X.2022.02.006

您当前的位置：

首页 >

文章列表页 >

Individualized Pharmaceutical Care for a Child with Infective Endocarditis and Osteomyelitis

更新时间：2022-11-03

- Individualized Pharmaceutical Care for a Child with Infective Endocarditis and Osteomyelitis
- Vol. 28, Issue 2, Pages: 19-23(2022)
- 作者机构：
  
  1. 吉林大学第二医院,长春,130041
  2. 吉林大学校医院,长春,130012
- 作者简介：
- 基金信息：
- DOI：10.13407/ j.cnki.jpp.1672-108X.2022.02.006
  CLC：
- Published：2022，
  
  Published Online：10 February 2022，
扫描看全文
Wang Siyun, Liang Dandan, Ma Jiulong, et al. Individualized Pharmaceutical Care for a Child with Infective Endocarditis and Osteomyelitis. [J]. 28(2):19-23(2022)
DOI：

Wang Siyun, Liang Dandan, Ma Jiulong, et al. Individualized Pharmaceutical Care for a Child with Infective Endocarditis and Osteomyelitis. [J]. 28(2):19-23(2022) DOI： 10.13407/ j.cnki.jpp.1672-108X.2022.02.006.

摘要

目的：探讨1例感染性心内膜炎伴骨髓炎儿童患者的治疗药物应用决策及基于血药浓度监测的万古霉素剂量调整，分析临床药师在抗感染治疗中的作用。方法：对1例罹患感染性心内膜炎伴骨髓炎患儿实施药学监护和药学会诊，同时根据万古霉素血药浓度监测结果进行个体化给药调整。结果：在治疗过程中，患儿出现药物相关性超敏反应、病情反复和血药浓度异常等情况，在临床药师多次参与会诊和全程监护下，抗感染治疗好转出院。结论：临床药师在抗感染治疗优化方案、药物不良反应评估处理、血药浓度监测和个体化给药调整等方面具有专业优势，在儿童严重感染的治疗中发挥着重要作用，充分体现了临床药师的职业价值。

Abstract

Objective: To explore the decision-making of therapeutic drug application and the dose adjustment of vancomycin based on blood concentration monitoring in a child with infective endocarditis and osteomyelitis

so as to analyze the role of clinical pharmacists in anti-infective treatment. Methods: Omnidirectional pharmaceutical care and pharmaceutical consultation were performed on a child with infective endocarditis and osteomyelitis. Individualized drug administration regimen was adjusted according to the results of vancomycin blood concentration. Results: During the treatment

situations such as the drug-related hypersensitivity reaction

recrudescent symptoms and abnormal blood concentration were observed. With the participation of clinical pharmacists for many consultations and the whole process of monitoring

the child was discharged from the hospital after improved anti-infective treatment. Conclusion: Clinical pharmacists have professional advantages in anti-infective treatment optimization

adverse drug reaction assessment and management

blood concentration monitoring and individualized drug administration adjustment

and play an important role in the treatment of severe infection in children

fully reflecting the professional value of clinical pharmacists.

关键词

儿童感染性心内膜炎万古霉素血药浓度监测药学监护

Keywords

childrennfective endocarditisancomycintherapeutic drug monitoringpharmaceutical care

references

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Eleven Cases of Vancomycin-Induced Drug Fever in Children and Literature Review

A Case Report of Liver Failure in a Child Induced by Ibuprofen

Analysis of Pharmaceutical Care on the Use of Voriconazole in Pediatric Liver Transplantation Patients Younger Than 2 Years of Age

Treatment of Cerebral Venous Thrombosis in a Child with Warfarin Based on Gene Polymorphism

Pharmaceutical Care for One Child with Refractory Mycoplasma Pneumoniae Pneumonia Complicated with Pulmonary Embolism by Clinical Pharmacists

Related Author

Peng Jing

Xu Hua

Li Xinlin

Li Qiaoling

Wang Juping

Li Zhiling

Liu Hongxia

Huang Jianquan

Related Institution

Wuhan Children’s Hospital, Tongji Medical College, Huazhong University of Science & Technology

Shanghai Children’s Hospital, Children’s Hospital of Shanghai Jiao Tong University School of Medicine

Henan Children’s Hospital

Beijing Friendship Hospital, Capital Medical University

Xiangya Hospital, Central South University

⁰